| Cast list |
| Robert Downey Jr. | as | Tony Stark (voice) |
| Terrence Howard | as | Col. James 'Rhodey' Rhodes (voice) |
| Shaun Toub | as | Yinsen (voice) |
| Dimitri Diatchenko | as | Boris Bullski /Titanium Man (voice) |
| Gavin Hammon | as | Bruno Horgan /Melter (voice) |
| Zach McGowan | as | Marc Scarlotti /Whiplash / Stark Engineer (voice) |
| Meredith Monroe | as | Virginia 'Pepper' Potts (voice) |
| Stephen Stanton | as | Iron Man / Pilot / Engineer / Afghan Soldier (voice) |
| Gillon Stephenson | as | Jarvis (voice) |
| Fred Tatasciore | as | Obadiah Stane /Iron Monger / Maggia Soldier / Afghan Soldier / AIM President (voice) |
| Courtenay Taylor | as | Whitney Frost /Madame Masque (voice) |
