| Cast list |
| Joe Buck | as | Himself - Play-by-Play Announcer |
| Tim McCarver | as | Himself - Color Commentator |
| Steve Lyons | as | Himself - Field Reporter |
| Jeanne Zelasko | as | Herself - Pre-Game Host |
| Kevin Kennedy | as | Himself - Pre-game Analyst |
| Roberto Alomar | as | Himself - AL Second Baseman, Cleveland Indians |
| Moises Alou | as | Himself - NL Right Fielder, Houston Astros |
| Luis Aparicio | as | Himself - Ceremonial 1st Pitch |
| Rich Aurilia | as | Himself - NL Starting Shortstop, San Francisco Giants |
| Dusty Baker | as | Himself - NL Coach, San Francisco Giants |
| Lance Berkman | as | Himself - NL Left Fielder, Houston Astros |
| Bruce Bochy | as | Himself - NL Coach, San Diego Padres |
| Barry Bonds | as | Himself - NL Starting Left Fielder, San Francisco Giants |
| Bret Boone | as | Himself - AL Starting Second Baseman, Seattle Mariners |
| Ralph Branca | as | Himself - NL Honorary Co-Captain |
| John Burkett | as | Himself - NL Pitcher, Atlanta Braves |
| Mike Cameron | as | Himself - AL Center Fielder, Seattle Mariners |
| Sean Casey | as | Himself - NL First Baseman, Cincinnati Reds |
| Orlando Cepeda | as | Himself - Ceremonial 1st Pitch |
| Tony Clark | as | Himself - AL First Baseman, Detroit Tigers |
| Roger Clemens | as | Himself - AL Starting Pitcher, New York Yankees |
| Cliff Floyd | as | Himself - NL Left Fielder, Florida Marlins |
| Freddy Garcia | as | Himself - AL Pitcher, Seattle Mariners |
| Jason Giambi | as | Himself - AL First Baseman, Oakland Athletics |
| Brian Giles | as | Himself - NL Left Fielder, Pittsburgh Pirates |
| Troy Glaus | as | Himself - AL Third Baseman, Anaheim Angels |
| Juan Gonzalez | as | Himself - AL Starting Right Fielder, Cleveland Indians |
| Luis Gonzalez | as | Himself - NL Starting Center Fielder, Arizona Diamondbacks |
| Vladimir Guerrero | as | Himself - NL Right Fielder, Montreal Expos |
| Cristian Guzman | as | Himself - AL Shortstop - Minnesota Twins |
| Mike Hampton | as | Himself - NL Pitcher, Colorado Rockies |
| Todd Helton | as | Himself - NL Starting First Baseman, Colorado Rockies |
| Ferguson Jenkins | as | Himself - Ceremonial 1st Pitch |
| Derek Jeter | as | Himself - AL Shortstop - New York Yankees |
| Charles Johnson | as | Himself - NL Catcher, Florida Marlins |
| Randy Johnson | as | Himself - NL Starting Pitcher, Arizona Diamondbacks |
| Chipper Jones | as | Himself - NL Starting Third Baseman, Atlanta Braves |
| Jeff Kent | as | Himself - NL Starting Second Baseman, San Francisco Giants |
| Ryan Klesko | as | Himself - NL First Baseman, San Diego Padres |
| Jon Lieber | as | Himself - NL Pitcher, Chicago Cubs |
| Juan Marichal | as | Himself - Ceremonial 1st Pitch |
| Edgar Martinez | as | Himself - AL Starting Designated Hitter, Seattle Mariners |
| Joe Mays | as | Himself - AL Pitcher, Minnesota Twins |
| Eric Milton | as | Himself - AL Pitcher, Minnesota Twins |
| Matt Morris | as | Himself - NL Pitcher, St. Louis Cardinals |
| Tony Muser | as | Himself - AL Coach, Kansas City Royals |
| Jeff Nelson | as | Himself - AL Relief Pitcher, Seattle Mariners |
| Phil Nevin | as | Himself - NL Third Baseman, San Diego Padres |
| John Olerud | as | Himself - AL Starting First Baseman, Seattle Mariners |
| Magglio Ordóñez | as | Himself - AL Right Fielder, Chicago White Sox |
| Chan Ho Park | as | Himself - NL Pitcher, Los Angeles Dodgers |
| Troy Percival | as | Himself - AL Relief Pitcher, Anaheim Angels |
| Tony Perez | as | Himself - Ceremonial 1st Pitch |
| Andy Pettitte | as | Himself - AL Pitcher, New York Yankees |
| Mike Piazza | as | Himself - NL Starting Catcher, New York Mets |
| Lou Piniella | as | Himself - AL Coach, Seattle Mariners |
| Jorge Posada | as | Himself - AL Catcher, New York Yankees |
| Kirby Puckett | as | Himself - AL Honorary Captain |
| Albert Pujols | as | Himself - NL Third Baseman, St. Louis Cardinals |
| Paul Quantrill | as | Himself - AL Pitcher, Toronto Blue Jays |
| Manny Ramirez | as | Himself - AL Starting Left Fielder, Boston Red Sox |
| Rick Reed | as | Himself - NL Pitcher, New York Mets |
| Cal Ripken | as | Himself - AL Starting Third Baseman, Baltimore Orioles |
| Mariano Rivera | as | Himself - Al Relief Pitcher, New York Yankees |
| Alex Rodríguez | as | Himself - AL Starting Shortstop, Texas Rangers |
| Ivan Rodriguez | as | Himself - AL Starting Catcher, Texas Rangers |
| Jimmy Rollins | as | Himself - NL Shortstop, Philadelphia Phillies |
| Kazuhiro Sasaki | as | Himself - AL Relief Pitcher, Seattle Mariners |
| Curt Schilling | as | Himself - NL Pitcher, Arizona Diamondbacks |
| Jeff Shaw | as | Himself - NL Relief Pitcher, Los Angeles Dodgers |
| Ben Sheets | as | Himself - NL Pitcher, Milwaukee Brewers |
| Sammy Sosa | as | Himself - NL Starting Right Fielder, Chicago Cubs |
| Mike Stanton | as | Himself - AL Relief Pitcher, New York Yankees |
| Ichiro Suzuki | as | Himself - AL Starting Center Fielder, Seattle Mariners |
| Mike Sweeney | as | Himself - AL First Baseman, Kansas City Royals |
| Bobby Thomson | as | Himself - NL Honorary Co-Captain |
| Joe Torre | as | Himself - AL Manager, New York Yankees |
| Bobby Valentine | as | Himself - NL Manager, New York Mets |
| Greg Vaughn | as | Himself - AL Outfielder, Tampa Bay Devil Rays |
| Billy Wagner | as | Himself - NL Relief Pitcher, Houston Astros |
| Larry Walker | as | Himself - NL Starting Designated Hitter, Colorado Rockies |
| Bernie Williams | as | Himself - AL Center Fielder, New York Yankees |
