| Cast list |
| Jerry Garcia | as | Himself - Grateful Dead |
| Donna Godchaux | as | Herself - Grateful Dead (as Donna Jean Godchaux) |
| Keith Godchaux | as | Himself - Grateful Dead |
| Mickey Hart | as | Himself - Grateful Dead |
| Bill Kreutzmann | as | Himself - Grateful Dead |
| Phil Lesh | as | Himself - Grateful Dead |
| Bob Weir | as | Himself - Grateful Dead |
| The New Riders of the Purple Sage | as | Themselves |
| Dan Aykroyd | as | Elwood Blues / Himself - Midnight Countdown |
| John Belushi | as | Jake Blues |
| Steve Cropper | as | Himself - The Blues Brothers Band |
| Donald Dunn | as | Himself - The Blues Brothers Band |
| Steve Jordan | as | Himself - The Blues Brothers Band |
| Tom Malone | as | Himself - The Blues Brothers Band |
| Lou Marini | as | Himself - The Blues Brothers Band |
