| Cast list |
| Billy West | as | Philip J. Fry /Prof. Hubert J. Farnsworth /Dr. Zoidberg /Zapp Brannigan /Richard Nixon /Leo Wong /Moon Farmer /M-5438 /Mr. Kroker /Judge Ron Whitey / Carnival Barker / Superhero / Land Squid (voice) |
| Katey Sagal | as | Turanga Leela (voice) |
| John Di Maggio | as | Bender /Randy Munchnick /URL / Calculon's Manservant / Funkalistics Lead Singer / Guard #1 (voice) (as John DiMaggio) |
| Tress MacNeille | as | Crazed Fan / Bender's First Born Son / Hattie McDoogal /Linda /The Grand Midwife / Pocket Pal /Thog /Gladys Lennox /Suicide Booth /Monique /Petunia /Mrs. Kroker /Morgan Procter (voice) |
| Maurice LaMarche | as | Kif Kroker /Calculon /Morbo /Schlomo / SportsBot 5000 /Lrrr /Destructor /Horrible Gelatinous Blob /Hedonismbot /Fishy Joseph Gillman /Harold Zoid /King Kong / Guard #2 (voice) |
| Phil LaMarr | as | Hermes Conrad / Horse Repair Robot /Ndulu /Robot 1-X /Billionairebot /Bolt Rollands (voice) |
| Lauren Tom | as | Amy Wong /Inez Wong (voice) |
| David Herman | as | Dr. Ogden Wernstrom / Plastic Surgeon Robot / British Robot / Coffee Enema Robot /Chu /Warden Vogel / Three-Eyed Zebra /Fatbot / Giant Medium-Sized Ant /Mayor C. Randall Poopenmeyer /Pazuzu (voice) |
| Dan Castellaneta | as | The Robot Devil (voice) |
| David Cross | as | Yivo (voice) |
| Stephen Hawking | as | Himself (voice) |
| Brittany Murphy | as | Colleen O'Hallahan (voice) |
