| Cast list | | James Mason | as | Dr. John Polidori | | Leonard Whiting | as | Dr. Victor Frankenstein | | David McCallum | as | Dr. Henry Clerval | | Jane Seymour | as | Agatha/Prima | | Nicola Pagett | as | Elizabeth Fanschawe | | Michael Sarrazin | as | The Creature | | Michael Wilding | as | Sir Richard Fanshawe | | Clarissa Kaye-Mason | as | Lady Fanschawe (as Clarissa Kaye) | | Agnes Moorehead | as | Mrs. Blair | | Margaret Leighton | as | Francoise DuVal | | Ralph Richardson | as | Mr. Lacey | | John Gielgud | as | Chief Constable (Police) | | Tom Baker | as | Sea Captain | | Dallas Adams | as | Felix | | Julian Barnes | as | Young Man |
| | Crew list: | | Jack Smight (Director) | | Don Bachardy (Writer) | | Christopher Isherwood (Writer) |
|
