| Cast list |
| William Ash | as | Simon (segment Standing Room Only) |
| Nicholas Audsley | as | Larry's Son (segment Standing Room Only) |
| Paul Bettany | as | Y (segment Euston Road) |
| Tilly Blackwood | as | Call Girl (segment Euston Road) |
| Cate Blanchett | as | Julie-Anne (segment Bangers) |
| Billy Boyd | as | Sniper (segment Sniper 470) |
| Charlie Condou | as | X (segment Euston Road) |
| Delilah Cotto | as | Angela (segment A Whole New Day) |
| Lynette Curran | as | Mother (segment Bangers) |
| Sophie Dahl | as | Veronica (segment Standing Room Only) |
| Louise Delamere | as | Woman (segment Euston Road) |
| Ned Eisenberg | as | Jimmy (segment A Whole New Day) |
| Nabil Elouhabi | as | Barman (segment Euston Road) |
| Michael Gambon | as | Larry (segment Standing Room Only) |
| James Gandolfini | as | Vincent (segment A Whole New Day) |
| Gabriel García | as | The Baby (segment A Whole New Day) |
| Philip Herbert | as | (segment New Year's Eve) |
| Hugh Jackman | as | Roger (segment Standing Room Only) |
| Keira Knightley | as | Leah (segment New Year's Eve) |
| Amit Lahav | as | (segment New Year's Eve) |
| Maureen Lipman | as | Larry's Wife (segment Standing Room Only) |
| Joanna Lumley | as | Last in Line (segment Standing Room Only) |
| Stephen Mangan | as | (segment New Year's Eve) |
| Mary Elizabeth Mastrantonio | as | Maria (segment Standing Room Only) |
| Kathrine Narducci | as | Carol (segment A Whole New Day) |
| Bohdan Poraj | as | (segment New Year's Eve) |
| Andy Serkis | as | Granny/Rastafarian/Hunter Jackson (segment Standing Room Only) |
