| Cast list |
| Patrick Stewart | as | Professor Charles Xavier (voice) |
| Hugh Jackman | as | Wolverine (voice) |
| Alan Cumming | as | Nightcrawler (voice) |
| Shawn Ashmore | as | Iceman (voice) |
| Tyler Mane | as | Sabretooth (voice) |
| Eric Dane | as | Multiple Man (voice) |
| Vyvan Pham | as | Lady Deathstrike (voice) (as Vyan Pham) |
| Dwight Schultz | as | Magneto / Additional Voices (voice) |
| Gregg Berger | as | Beast / Additional VO (voice) |
| Debra Wilson | as | Storm (voice) |
| Steve Van Wormer | as | Pyro / Additional Voices (voice) (as Steve Van Womer) |
| Keone Young | as | Silver Samurai (voice) |
| Brad Abrell | as | Colossus / Additional Voices (voice) |
| James Arnold Taylor | as | Cyclops / Additional Voices (voice) |
| Steve Blum | as | Jason Stryker / Additional Voices (voice) (as Steven Jay Blum) |
