| Cast list |
| Arsenio Hall | as | Apartment Victim (segment "Mondo Condo") (as Arsenio) |
| Donald F. Muhich | as | Easterbrook (segment "Pethouse Video") |
| Monique Gabrielle | as | Taryn Steele (segment "Pethouse Video") |
| Lou Jacobi | as | Murray (segment "Murray in Videoland") |
| Erica Yohn | as | Selma (segment "Murray in Videoland") |
| Debby Davison | as | Weatherperson (segment "Murray in Videoland") |
| Rob Krausz | as | Floor Manager (segment "Murray in Videoland") |
| Phil Hartman | as | Baseball Announcer (segment "Murray in Videoland") |
| Corey Burton | as | Anchorman (segment "Murray in Videoland")/TV Announcer (segment "Amazon Women on the Moon")/Announcer (segment "Silly Pate") |
| Michelle Pfeiffer | as | Brenda Landers (segment "Hospital") |
| Peter Horton | as | Harry Landers (segment "Hospital") |
| Griffin Dunne | as | Doctor (segment "Hospital") |
| Brian Ann Zoccola | as | Nurse (segment "Hospital") |
| Joe Pantoliano | as | Sy Swerdlow (segment "Hairlooming") |
| Stanley Brock | as | Customer (segment "Hairlooming") |
